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Excessive ROS production also leads to mitochondrial dysfunction, DNA damage, and potential alterations in neurotransmitter signaling [60-62]

"These people are waking up in the morning and taking their pill with a glass of water, and then they do their normal daily routine half an hour later and move on with their life." He also called the company's drug the "most efficacious pill," saying that no other products in development have been able to show its same level of weight loss in a late-stage trial

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Mavropoulos JC, Yancy WS, Hepburn J, Westman EC

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In clinical practice, the most frequent question will be to determine which drug to add to the incretin that a patient with MASH is already receiving