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These signaling behaviors are closely associated with dermal and connective environments where coordinated peptide activity contributes to integrated structural organization and adaptive cellular response

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Increasing evidence has revealed the crucial role of IFN--CXCL9/10-CXCR3 pathway-related proteins in epidermal recruitment and CD8 + T lymphocyte-mediated melanocyte destruction during the progression of vitiligo [211,212,213]