According to the method disclosed by the invention, the crude semaglutide is prepared by carrying out liquid-phase one-step reaction on two segments of fragment peptides in a liquid phase, in the final liquid chromatography purification step, impurities are not defective peptides lacking one or more amino acids, but are uncondensed partial fragments, the purification difficulty is not caused, in addition, the uncondensed partial peptide fragments can be recycled, and the cost is saved
References Huang S, Dong Q, Che S, Li R, Tang KHD
Crucial Role of Fatty Acid Oxidation in Asthmatic Bronchial Smooth Muscle Remodelling
Cell Mechanisms (00:25:28) Sponsor: Eight Sleep (00:26:46) Tool: 3 x 5 Protocol
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This information should be interpreted with a qualified healthcare provider to inform initial dosing and titration decisions