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-oxidation initiation: After acyl-CoA enters the mitochondrial matrix, it is gradually degraded through the -oxidation pathway, generating 1 molecule of FADH, 1 molecule of NADH, and 1 molecule of Acetyl-CoA (acetyl-COA) in each cycle

*Correspondence: Xiao-Yuan Mao, [email protected] These authors have contributed equally to this work This article was submitted to Neuropharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Carl, A

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Liao, C