Long-term continuous use data is limited, but occasional cycles appear safe
To that end, I am one of the principal investigators of MSKs telehealth research center, MATCHES, which stands for Making Telehealth Delivery of Cancer Care at Home Effective and Safe. In August of 2022, the National Cancer Institute (NCI) awarded MSK a grant to create this telehealth research center
Important: Based on the patients overall health, type, and severity of the condition, the symptoms explained above may vary in severity from patient to patient
these variations might also explain the difference in cardiovascular effect observed in large-scale cardiovascular outcome trials, in which certain GLP1RAs were shown to have a positive effect on cardiovascular outcomes
Male patients, nonetheless, exhibit higher vulnerability to serious adverse events (OR = 2.196) compared to females, warranting additional vigilance
For example, semaglutide can help you lose 15% of your weight in 68 weeks, while an older drug, Contrave, has been shown to result in closer to a 5% weight loss