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Discontinue creatine supplementation and increase water intake to 3-4 liters daily for one week

It's advisable to avoid alcohol during dose escalation periods or when experiencing gastrointestinal symptoms

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Unfortunately, there is a clear contradiction between the exact evidence supporting its efficacy and safety, and the hype around its depigmentary properties, with pharma-cosmeceuticals inundating dermatology therapeutics with glutathione tablets, capsules, topical preparations and parenteral preparations across the globe [9]

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This reflects a growing sophistication among consumers, who are using public forums to crowdsource knowledge, compare experiences, and share insights about emerging options