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Result: significant muscle loss (20-30% of weight lost)

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(4,12) In the late 1970s, roughly 3.8 percent of the U.S

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A 42-year-old female with longstanding profound fatigue, chronic pain, asthma, multiple food intolerances, GI symptoms including diarrhea, urticaria, food cravings, weight gain, and migraine who was essentially housebound due to constant exhaustion (she estimated 30% of normal energy) took tirzepitide at 3.75 mg principally to address obesity

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