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Additionally, semaglutide markedly elevated the expression levels of intracellular antioxidants GSH and SOD, compared to the ischemia-hypoxia group (Figures 1B, C)

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47 Exendin-4 significantly increased amyloid protein (A)-induced reduction in mitochondrial function, integrity, respiratory control rate, and mitochondrial P/O ratio in all brain regions and decreased A-induced increase in the mitochondrial complex enzyme-I, IV, and V activities in all brain regions