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May 2013;24(3):592-593

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doi:10.3389/fpsyt.2016.00033 Li Q, Ouyang X, Lin J

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We highlight how single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics have unveiled unprecedented cellular heterogeneity, delineated pathogenic trajectories like maladaptive tubular cell states, and established immune dysregulation as central to disease progression