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Overexpressing adiponectin in leptin-deficient ( ob/ob) mice results in decreased plasma glucose and insulin levels, increased liver and muscle insulin sensitivity (which is thought to be due to decreased fat content), significantly increased mass of adipose tissue (these mice were morbidly obese) and a highly significant lowering of plasma triglycerides and FFAs

doi: 10.1177/0023677215571192

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Most users notice reduced appetite within days to weeks of starting treatment

GPs may prescribe medications like Orlistat to aid weight loss in appropriate patients, along with recommending lifestyle interventions like dietary changes and exercise

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