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Moreover, existing evidence demonstrated that inhibiting the phosphorylation of PI3K could increase AQP4 expression, which suggested that PI3K/Akt involves in the regulation of AQP4 (Song et al., 2018)

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Exogenous histone deacetylase inhibitors (HDACi), such as butyrate and trichostatin A, synergize with Vitamin D to enhance cathelicidin and CD14 expression, simultaneously increasing the bactericidal capacity of keratinocytes against Staphylococcus aureus and elevating histone H4 acetylation levels [127]

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Arch Pharm 350(12):e1700198 [DOI] [PubMed] [Google Scholar] Koyiit UM, Budak Y, Grdere MB, Ertrk F, Yencilek B, Taslimi P, Gulin , Ceylan M (2018) Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles

Int J Biol Macromol 293:139216