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34,35 Subsequently, GLP-1 undergoes enzymatic degradation facilitated by dipeptidyl peptidase IV (DPP-4), leading to the loss of its biological efficacy

Additionally, the medications' effects on nausea and the gastrointestinal system may create aversions to certain foods or alter the subjective experience of eating

Common, expected injection site reactions include: Redness or erythema at the injection site Mild swelling or oedema Bruising or haematoma formation Itching or mild discomfort Small, firm nodules beneath the skin (particularly if sites are not rotated) These reactions are typically self-limiting

Along with giving you relief, that means some people may be able to stop treatment for a condition

As a triple receptor agonist targeting GLP-1, GIP, and glucagon pathways simultaneously, it produced weight reduction numbers in clinical trials that made even seasoned researchers pause