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Here is a good article on it from the Cleveland Clinic
Ceramides, which are elevated in both GWS and ME/CFS, are implicated in the activation of pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor (TNF-) within immune cells such as macrophages, as well as in serum (Germain et al., 2020
40,66 Leucine also positively regulates insulin secretion as it generates ATP via the Krebs cycle by allosterically stimulating glutamic dehydrogenase and producing alpha-ketoglutarate
Toxins (Basel) 11 (656), 128
Decreased GSH levels have been shown to activate NF-kB, further impairing mitochondrial function and creating a vicious cycle
It mitigates and treats these diseases
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