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This approval was granted due to Phase 3 trial data which showed benefit in both weight-related outcomes, as well as hunger reduction, in patients with BBS

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Semaglutide could be more effective than other GLP-1R agonists in its neuroprotective action due to its longer half-life of 7 days 48 , and could elicit fewer immune responses in patients due to its 94% homology to human GLP-1 protein 18