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The letter did not cite manufacturing, safety, or medication quality problems

Signs of potential degradation or contamination include: Discolouration yellowing, browning, or any unusual colour change Clumping or caking which may indicate moisture ingress Visible particulates or foreign matter Unusual odour though peptides are generally odourless, any detectable smell may indicate microbial contamination After reconstitution , a degraded or contaminated solution may appear cloudy, discoloured, or contain visible particles

Very recently, Ravussin et al

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Phase 2 data showed the 8mg combined group achieved 22.8% mean weight reduction at 48 weeks, which is only 1.4 percentage points less than the 12mg group

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