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signs like rash, itching, or swelling would necessitate immediate medical attention

We first studied hyperpolarized [1- 13 C]dehydroascorbate in the normal rat brain, demonstrating its robust conversion to [1- 13 C]vitamin C, consistent with rapid transport of the oxidized form across the blood-brain barrier

Mice treated with 150 mg/kg (about 900 mg for an adult human) or 300 mg/kg (about 1,800 mg for an adult human) of the extract had total cholesterol reductions of 14.2% and 7.1%, respectively, compared with the control group

In patients with bulimia or anorexia nervosa, vitamin B 12 deficiency also can be related to diet

There is no real evidence to suggest that there are toxicity levels with B12

Journal of Neuroscience Research, 83(7), 1252-1261