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Human trials showed that in people with high-risk features, treatment with minocycline reduced in 6 months the risk of conversion to MS, decreased lesion volume, and showed the absence of new enhancing lesions, but this effect did not last beyond 24 months of study (Preiningerova et al., 2022)

Y., Chang, S

Key regions include the amygdala, which processes sensory input related to threats, the prefrontal cortex, and the ventral hippocampus, which is involved in processing contextual information (Lezak et al., 2022

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