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If you are taking the medication as prescribed, following dietary guidance, sleeping adequately and have ruled out metabolic or endocrine barriers, yet still see minimal weight loss after 12 to 16 weeks, it says it is appropriate to discuss next steps

Inflammatory markers decrease, potentially reducing vascular inflammation

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doi.org/10.1056/NEJMoa2032183 Medically Reviewed by Karla K

Epub 2021 Feb 10

Pancreatic cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics