Meeting Highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 8-11 April 2024
While the impact of GLP-1 RAs on cardiovascular outcomes has been shown to be directly correlated with the reduction in A1c, these agents exhibit pleiotropic effects [54]
Combining GLP1-RAs/SGLT2is for glucose control could be more effective than other antidiabetic combinations
Alternative Treatments and Next Steps If a patient experiences a confirmed allergic reaction to a GLP-1 agonist, discontinuation of the medication is necessary, and alternative treatment strategies must be considered
GLP-1s are generally safe, but some drugs have been withdrawn from the market due to long-term risks
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