These included nausea (reported by approximately 30-40% of participants on higher doses), diarrhea, vomiting, constipation, and abdominal discomfort
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND trial)
From a broader standpoint, starting with the 2 mg dose also set the stage for understanding long-term tolerability
TLR4 mutation protects neurovascular function and cognitive decline in high-fat diet-fed mice
The glucagon receptor component is the critical differentiator: activation drives hepatic fat oxidation, increased energy expenditure, and thermogenesismechanisms absent in dual or single agonists
Fatigue affects some people, particularly in the first month