Industry researchers estimate that while about 12% of United States citizens have used a GLP-1 medication for weight loss, 54% of adults who have taken GLP-1s say it was difficult to afford, and 53% say it was still too expensive even if they received insurance coverage for the medication
Aroda VR, Blonde L, Pratley RE
In the retatrutide trial data above, dysesthesia jumped from 8.8% at the 9 mg dose to 20.9% at the 12 mg dosea pattern that mirrors whats been seen with another GLP-1 medication at a higher dose
Read our deep-dive guide: Pepcid vs Prilosec: The Difference & The GLP-1 "PPI Trap" Your Pharmacy Shopping List: Famotidine: (Generic Pepcid AC) The ideal "Goldilocks" solution for GLP-1 users
Still, many doctors prescribe them off-label to help patients manage their weight because the active ingredient is the same as in Wegovy and Zepbound, just at a different dose
FAQS Is Tirzepatide safe for long-term use