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In AD, the A protein exists as insoluble aggregates that can form larger plaques called amyloid plaques or senile plaques, which are deposited in the brain and interfere with the function of nerve cells (Roher et al., 1996)

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GSHGSSG redox cycle The reversible conversion between glutathione (GSH) and its oxidized form, glutathione disulfide (GSSG), constitutes one of the most core cellular redox buffering systems