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To improve the pharmacokinetic profile and further explore the therapeutic potential of such an endogenously based GLP-1R/GcgR co-agonist, a DPP-IV-resistant OXM analogue was developed by adding a d-stereoisomer of serine at position 2 and a cholesterol moiety to the C-terminal domain

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Other treatments may be better suited for those cases

However, oocytes treated with Epitalon displayed a significantly lower rate of CG distribution abnormalities at both 12 and 24 hours

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The entire cohort median of the glycated hemoglobin was 6.6% (range 4.88.8%)