The effect of concomitant use of statins, NSAIDs, low-dose aspirin, metformin and beta-blockers on outcomes in patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis
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This has implications for how to design human albumin-fused biologics, as QMP engineering may ensure a long plasma half-life, increased target exposure, and enhanced efficacy, despite potential C-terminal cleavage post-administration
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