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IGFBP-3 is the major carrier protein for circulating IGF-1, and suppression has implications for endogenous IGF-1 bioavailability post-cycle

Senior leaders at Greggs and Leon have both commented on the need to rethink portion sizes in the GLP-1 era

The difference in total weight loss was also striking: after about two years, the surgical patients had lost an average of 28.3% of their starting body weight, while those treated with GLP-1s lost an average of 10.3%

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Moderate Caloric Deficit:** GLP-1 peptides naturally reduce appetite, but bodybuilders should ensure they are not in an extreme deficit

Yasuda H, Yoshida K, Yasuda Y, Tsutsui T