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Activation of 3-AR via Gs cAMP PKA phosphorylation of hormone-sensitive lipase (HSL) leads to: Splitting of triglycerides into free fatty acids + glycerol Release of fatty acids from adipose tissue into the blood Increased oxidation of fatty acids in mitochondria (muscle, liver) Heffernan et al

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Brameld K

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Nausea affects approximately 20-30% of patients, typically emerging within days of the first injection and often diminishing over 2-4 weeks as tolerance develops

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& Lindvall, O

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