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The limited net benefits of metformin for PCOS are why alternatives like Inositol and Berberine are becoming more popular

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Creatine increases serum creatinine (a kidney function marker), and semaglutide can affect fluid balance and kidney perfusion through appetite suppression and weight loss

Additionally, patients should be encouraged to combine these medications with healthy lifestyle changes

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In a pediatric clinical trial, rash was reported in 3% of WEGOVY-treated patients and 0% of placebo-treated patients, and urticaria was reported in 3% of WEGOVY-treated patients and 0% of placebo-treated patients