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The pain worsens with certain neck movements and often responds poorly to standard headache medications because the root problem sits in the spine, not the head

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Phosphorylation of 4E-BP1 results in release of eIF4E, which is required for binding of mRNA to the ribosome

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48 h post-transfection, cells were pelleted and resuspended (~1.5 g packed volume) into 5 mL membrane preparation buffer followed by homogenisation with a polytron homogeniser at 4 C