Excess FFAs impair insulin signaling and promote inflammation, further worsening insulin resistance
Final Verdict Highly versatile and effective for both physical and mental boosts
A total of 1,961 adult participants with a BMI of at least 30 or at least 27 with at least one weight-related comorbidity were randomized to receive either semaglutide (2.4 mg) or placebo, administered subcutaneously once weekly, along with lifestyle intervention
Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure
Post-marketing surveillance and observational studies have raised some concern, prompting regulatory reviews
The dental risks associated with GLP-1s are manageable with good oral hygiene, hydration, and regular dental check-ins