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Eli Lilly, the manufacturer, moved it into phase 3 trials
This phase is less structured than the escalation but still requires attention to specific factors that affect ongoing success
Depending on dose, 64100% of retatrutide-treated individuals achieved at least 5% weight loss (a common benchmark for clinical success) versus 27% on placebo
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That variation is driving a lot of interest in understanding the underlying biology. Researchers hope that, over time, they will be able to predict who will benefit most based on genetics, environment and other biological factors
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