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Several other medications have been approved by the FDA for weight loss and the management of type 2 diabetes

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of drugs commonly used for the treatment of type 2 diabetes and, more recently, for weight management

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Understanding this mechanism helps explain why diet and exercise alone may feel less effective during this life stage

The candidates that exist in 2026 are: clinician judgment (the gold standard, but in short supply), expanded laboratory work (DEXA for body composition, CGM for glycemic patterns, metabolic panels of increasing sophistication), patient-reported priorities (the founder who tells you he cares about muscle is providing useful prior information), and, increasingly, genetics