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In that trial, 4,286 (24.3%) of patients had heart failure with 1,347 of those patients having heart failure with reduced ejection fraction dwarfing the small numbers studied in the initial trials mentioned previously

In fact, a 2022 study found that most people taking semaglutide gained much of the weight back within a year of stopping the medication

adults currently take GLP-1 for weight loss, up from 3 percent in 2024

Recognized for his work in MDLs and state court litigations

DOI: 10.1210/jendso/bvab048.030

Rather than focusing only on calorie reduction, established medical sources emphasize maintaining muscle, supporting recovery, and sustaining physical function during weight loss