For plan sponsors, these differences highlight the importance of balancing efficacy with tolerability, as side-effects can directly influence adherence and total cost of therapy
[2] However, once stores are depleted, symptoms can include fatigue, weakness, constipation, loss of appetite, and neurological changes such as numbness, tingling, balance problems, and cognitive difficulties
This may be just another good reason to increase your fruit and vegetable intake.
In 2022, another meta-analysis included 98 patients that had advanced HF and a BMI of at least 35 kg/m2, that underwent bariatric surgery [76]
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A systematic review of 76 different clinical trials looking at the risk of gallbladder disease for people taking GLP-1 agonists showed that there was an increase in risk for the development of gallbladder disease when taken at higher doses for long periods of time