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In the present work, we used metabolic profiling to determine potential biomarkers of tamoxifen resistance, and gene expression levels of enzymes important to these metabolites and then correlated the expression to the survival of patients receiving tamoxifen

Interestingly, despite the activation of caspases in late stages of parthanatos, caspase inhibitors cannot inhibit the parthanatos process except for blocking PARP1 activity, confirming that PARP1-mediated cell death is caspase-independent [137, 139]

Stimulatory nanoparticles can reprogramme antigen-presenting cells and enhance T-cell activation, as demonstrated in the 4T1 model [142]

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Research indicates schisandra may help normalize elevated liver enzymes and protect against various hepatotoxins while supporting overall liver resilience