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The urinary antiproliferative factor (APF), which has been recently identified in the context of IC, acts to hinder cell growth and disrupts the repair of the damaged or worn-away urothelium, leading to alterations in the barrier function of the bladder lining (Sant, 2002)

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doi: 10.1016/j.metabol.2009.05.014

Lacking FDA approval and recent extensive peer-reviewed data, its use for anti-aging, bodybuilding, or other non-FDA approved purposes is not evidence-based and carries substantial risks, including reported hypersensitivity reactions and unknown long-term endocrine disruption [fda.gov], [mayoclinic.org]