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Proc Natl Acad Sci U S A 106 : 48944899

All patients treated with opioids require careful and frequent reevaluation for signs of misuse, abuse, and addiction, because use of opioid analgesic products carries the risk of addiction even under appropriate medical use

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Furthermore, we would like to acknowledge the treating clinicians for their cooperation and the study participants for their willingness to take part in this research

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