Ipamorelin works through ghrelin receptor signaling and is often considered for recovery, fat loss support, body composition, and performance goals
10.1016/j.bbi.2015.06.021 Brain Behav
Sequential initiationadding one agent, allowing 48 weeks for tolerance to develop, then introducing the secondmay improve tolerability, particularly regarding gastrointestinal side effects from GLP-1 receptor agonists
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With dual and triple agonists, clinical studies are now achieving results that are otherwise only known from bariatric surgery