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Among them, GLP-1/GLP-1R signals have been investigated as treatment targets for inflammation-related diseases, given their anti-inflammatory functions

Baseline comorbidities included distinct diagnosis of any of the following (yes, no): hypertension, hyperlipidemia, atrial fibrillation and flutter, deep vein thrombosis or pulmonary embolism, chronic heart failure, dementia, CKD stage, depression, anxiety, smoking, neuropathic pain, atherosclerotic cardiovascular disease (ASCVD), and additional weight or obesity-related conditions

Mechanisms of PDPN Among patients with DN, 3050% develop neuropathic pain

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Insurance coverage is a challenge Insurance coverage is currently the biggest hurdle preventing PCOS patients from accessing GLP-1s, said Dr