GLP-1 agonists bind to the GLP-1 receptor and stimulate it to produce a physiological response, such as an increase in insulin sensitivity or appetite suppression
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[DOI] [PMC free article] [PubMed] [Google Scholar] 176.Bennuri S.C., Rose S., Frye R.E
Clinical trials have consistently demonstrated that gastrointestinal adverse effects occur in a substantial proportion of patients initiating tirzepatide therapy