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The diagnosis of MASLD is based on the confirmed presence of hepatic steatosis, determined by imaging techniques or biopsy, in combination with cardiometabolic risk factors such as obesity (i.e., elevated body mass index BMI), hypertension, IR, or dyslipidemia, while excluding significant alcohol consumption [18]

Tumor Necrosis Factor- (TNF )-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death

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EGCG dose-dependently inhibited NF- at higher concentrations of 50 to 300 M [36]