Wilding JPH, Batterham RL, Davies M et al (2022) Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension
The drugs, including semaglutide (Ozempic, Wegovy and Rybelsus), tirzepatide (Mounjaro and Zepbound) and retatrutide (still in clinical trials), are used to treat both diabetes and obesity
Craig: It's interesting
We highlight how single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics have unveiled unprecedented cellular heterogeneity, delineated pathogenic trajectories like maladaptive tubular cell states, and established immune dysregulation as central to disease progression
Interestingly, under certain conditions, Treg cells can undergo functional reprogramming and acquire a Th17-like phenotype
Glucagon-like peptide-1 receptor agonists (also known as GLP-1 medications) get their name from a natural hormone found in the body