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The full analysis set of all randomized individuals and the safety analysis set (all individuals receiving at least one dose of trial product) were the same and therefore used for all efficacy and safety evaluations

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Bcl-2 and Bax levels were determined utilizing rat B-cell CLL/lymphoma 2 and apoptosis regulator BAX ELISA kits from CUSABIO (Wuhan, China)

Demographic data included age, sex, and the presence of Carney syndrome

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Kaikai P, Thurnham D (1983) The influence of riboflavin deficiency on Plasmodium berghei infection in rats