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The main pharmacological effects and underlying mechanism of action of rutin contribute to its antioxidant capacity through the Nrf2/ARE and anti-inflammatory properties due to NF-B, COX-2, IL-6, and TNF- suppression

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NF-E2-related factor-2 (Nrf2) is a transcription factor that regulates the expression of antioxidant and phase II detoxifying enzymes

Cells were seeded at a density of 2 10 4 per well in 96-well transparent plates 24 h before treatment

One characteristic of a research chemical is that it is for laboratory research use only

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