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The combination with lemon verbena (as in Metabolaid) appears to be more effective than either ingredient alone, suggesting a synergistic relationship

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BMC Nephrol

Experimental studies in rodents have shown that circulating GLP-1, or its agonist exendin-4 (see below), can reach the brain as they can bind to blood-brain barrier-free circumventricular organs such as the subfornical organ close to the hypothalamus [68], and the area postrema in the brainstem [68-69]

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