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49,58 Considering that GLP-1RAs beneficial effects on MASLD may relate to improving systemic metabolism rather than direct hepatic effects, comparing hepatic benefits among different antidiabetic medications is meaningful
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As a result, most health insurance plans are unlikely to cover GLP-1 agonists for prediabetes
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It plays a documented role in neutralizing free radicals, supporting detoxification pathways, and maintaining cellular health
Similarly, 4-PBA strongly attenuated oxidative stress in a high-fat diet or ammonia nitrogen-induced liver injury related to its ER stress-inhibiting activity (Dong et al., 2022)
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