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Interestingly, treatment of patient derived erythroblasts and non-hemopoietic cells with HDACi sodium butyrate (NaBu) increased transcriptional upregulation of the G6PD gene, while having no effect on other genes in the glycolytic or PPP pathway

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Then, youll decrease to one injection per week or per month

To minimize these events, Sean Wharton, MD, director of the Wharton Medical Clinic in Toronto, and colleagues suggest the three Es: E ducation and explanation E scalation to an appropriate dose E ffective management of GI side effects. Patients should be counseled on means to decrease adverse event risk such as reducing meal size