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RAM reports honoraria from Eli Lilly, Novo Nordisk, Sanofi Aventis and Procter & Gamble for educational meetings and funding for investigator-initiated studies from Procter & Gamble and Pfizer

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The accumulation of misfolded proteins in the ER can trigger a stress response that leads to increased ROS production and inflammation, contributing to neuronal cell death (Fan et al., 2017

Metabolic studies Animals were given either 6 g/kg glucose or distilled water (2 mL/100 g body weight, n = 10 for all groups) by gavage every 6 h (at 06:20, 12:20, 18:20, and 24:20 h) for 38 days, defined as the long-term oscillating glucose (LOsG) or sham group

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