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This localization theoretically reduces systemic side effects and cancer concerns compared to long-acting analogs, though local effects may still influence surrounding tissues

Understand FDA Guidelines for Compounding Pharmacies While the FDA does not approve compounded medications, it does regulate compounding pharmacies through the Drug Quality and Security Act (DQSA)

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PLoS ONE 6 , e16144 (2011)

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Starting at the lowest dose, rather than diving in at the deep end, gives you the chance to see how the medication affects you and lowers your risk of having severe side effects