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Piya S, Bhattacharya S, Mu H, Lorenzi PL, McQueen T, Davis RE, Ruvolog V, Baran N, Qian Y, Crews C, Kantarjian HM, Andreeff M , Borthakur G

This extensive distribution, combined with rapid plasma clearance, suggests tissue binding or cellular uptake contributes to the peptide's pharmacological effects

Neuroendocrine normalization: Studies in aged animal models document normalized anterior pituitary function and restored luteinizing hormone and follicle-stimulating hormone pulsatility following administration

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