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It would be advisable to tell him / her that you have supplemented with B12 (since a high serum B12 level, in the ABSENCE of supplementation, can be indicative of other serious conditions, so your GP will need to know that the high level is probably due to supplements)

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They might not absorb it as well

The energy from B12 is steady and natural, not a jittery caffeine-style rush

References Efficacy and Safety of Omeprazole for the Treatment of Acid Peptic Disorders: A Systematic Review and Meta-Analysis The primary objective of this study was to compare the efficacy of omeprazole with other proton-pump inhibitors (PPIs) and placebo in treating acid peptic disorders (APDs)

The body regulates B12 absorption through intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its uptake in the terminal ileum